This is the public timetable for the Toronto, Hamilton & Buffalo Railway, effective April 25, 1965. The TH&B was a railway running between Waterford, ON and Welland, ON (the International Railway Bridge near Niagara Falls), with a branch to Port Maitland.
This very dynamic looking timetable featured a bold cover, a map of the route, and timetables between various points on the line and beyond.
One feature of the TH&B was its extensive connections to Canadian Pacific Railway and the New York Central.
Note how the same route has up to 4 different train numbers – for example CPR 321, TH&B 376, NYC 376 and NYC 16 between Toronto and New York City – because a passenger would travel over multiple railways.